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Exploring Aurone Derivatives as Potential Human Pancreatic Lipase Inhibitors through Molecular Docking and Molecular Dynamics Simulations

Inhibition of human pancreatic lipase, a crucial enzyme in dietary fat digestion and absorption, is a potent therapeutic approach for obesity treatment. In this study, human pancreatic lipase inhibitory activity of aurone derivatives was explored by molecular modeling approaches. The target protein...

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Detalles Bibliográficos
Autores principales:	Nguyen, Phuong Thuy Viet, Huynh, Han Ai, Truong, Dat Van, Tran, Thanh-Dao, Vo, Cam-Van Thi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587340/ https://www.ncbi.nlm.nih.gov/pubmed/33066044 http://dx.doi.org/10.3390/molecules25204657

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