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High-Throughput Screening for Inhibitors of the SARS-CoV-2 Protease Using a FRET-Biosensor

The global SARS-CoV-2 pandemic started late 2019 and currently continues unabated. The lag-time for developing vaccines means it is of paramount importance to be able to quickly develop and repurpose therapeutic drugs. Protein-based biosensors allow screening to be performed using routine molecular...

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Detalles Bibliográficos
Autores principales: Brown, Alistair S., Ackerley, David F., Calcott, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587356/
https://www.ncbi.nlm.nih.gov/pubmed/33066278
http://dx.doi.org/10.3390/molecules25204666