Cargando…

Inhibition of Coronavirus Entry In Vitro and Ex Vivo by a Lipid-Conjugated Peptide Derived from the SARS-CoV-2 Spike Glycoprotein HRC Domain

The emergence of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), the etiological agent of the 2019 coronavirus disease (COVID-19), has erupted into a global pandemic that has led to tens of millions of infections and hundreds of thousands of deaths worldwide. The development of th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Outlaw, Victor K., Bovier, Francesca T., Mears, Megan C., Cajimat, Maria N., Zhu, Yun, Lin, Michelle J., Addetia, Amin, Lieberman, Nicole A. P., Peddu, Vikas, Xie, Xuping, Shi, Pei-Yong, Greninger, Alexander L., Gellman, Samuel H., Bente, Dennis A., Moscona, Anne, Porotto, Matteo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587434/ https://www.ncbi.nlm.nih.gov/pubmed/33082259 http://dx.doi.org/10.1128/mBio.01935-20

Ejemplares similares

In vivo antiviral host transcriptional response to SARS-CoV-2 by viral load, sex, and age
por: Lieberman, Nicole A. P., et al.
Publicado: (2020)

Molecular Features of the Measles Virus Viral Fusion Complex That Favor Infection and Spread in the Brain
por: Mathieu, Cyrille, et al.
Publicado: (2021)

Subnanometer structure of an enveloped virus fusion complex on viral surface reveals new entry mechanisms
por: Marcink, Tara C., et al.
Publicado: (2023)

Sensitive Recovery of Complete SARS-CoV-2 Genomes from Clinical Samples by Use of Swift Biosciences’ SARS-CoV-2 Multiplex Amplicon Sequencing Panel
por: Addetia, Amin, et al.
Publicado: (2020)

Intermediates in SARS-CoV-2 spike–mediated cell entry
por: Marcink, Tara C., et al.
Publicado: (2022)

Spike Glycoprotein-Mediated Entry of SARS Coronaviruses
por: Wang, Lin, et al.
Publicado: (2020)

Human parainfluenza virus fusion complex glycoproteins imaged in action on authentic viral surfaces
por: Marcink, Tara C., et al.
Publicado: (2020)

Viral Entry Properties Required for Fitness in Humans Are Lost through Rapid Genomic Change during Viral Isolation
por: Iketani, Sho, et al.
Publicado: (2018)

Hijacking the Fusion Complex of Human Parainfluenza Virus as an Antiviral Strategy
por: Marcink, T. C., et al.
Publicado: (2020)

Biophysical characterization of HRC peptide analogs interaction with heptad repeat regions of the SARS-coronavirus Spike fusion protein core
por: Yan, Zhe, et al.
Publicado: (2006)

Intranasal fusion inhibitory lipopeptide prevents direct contact SARS-CoV-2 transmission in ferrets
por: de Vries, Rory D., et al.
Publicado: (2020)

Helicobacter pylori Stress-Response: Definition of the HrcA Regulon
por: Roncarati, Davide, et al.
Publicado: (2019)

Host Cell Membrane Capture by the SARS-CoV-2 Spike Protein Fusion Intermediate
por: Su, Rui, et al.
Publicado: (2023)

Electron Tomography Imaging of Surface Glycoproteins on Human Parainfluenza Virus 3: Association of Receptor Binding and Fusion Proteins before Receptor Engagement
por: Gui, Long, et al.
Publicado: (2015)

Erratum for Gui et al., Electron Tomography Imaging of Surface Glycoproteins on Human Parainfluenza Virus 3: Association of Receptor Binding and Fusion Proteins before Receptor Engagement
por: Gui, Long, et al.
Publicado: (2016)

Nebulized fusion inhibitory peptide protects cynomolgus macaques from measles virus infection
por: Reynard, Olivier, et al.
Publicado: (2022)

Interaction between the Hemagglutinin-Neuraminidase and Fusion Glycoproteins of Human Parainfluenza Virus Type III Regulates Viral Growth In Vivo
por: Xu, Rui, et al.
Publicado: (2013)

Rapid Screening for Entry Inhibitors of Highly Pathogenic Viruses under Low-Level Biocontainment
por: Talekar, Aparna, et al.
Publicado: (2012)

The Role of Early Diagnosis of Hepatorenal Cystic (HRC) Syndrome in Children-Clinical Trial
por: MATEESCU, DIANA ŞTEFANIA, et al.
Publicado: (2017)

GP38 as a vaccine target for Crimean-Congo hemorrhagic fever virus
por: Scher, Gabrielle, et al.
Publicado: (2023)

Nebulized fusion inhibitory peptide protects cynomolgus macaques from measles virus infection
por: Reynard, Olivier, et al.
Publicado: (2022)

Suppression of SARS-CoV entry by peptides corresponding to heptad regions on spike glycoprotein
por: Yuan, Kehu, et al.
Publicado: (2004)

Rapid and Flexible Platform To Assess Anti-SARS-CoV-2 Antibody Neutralization and Spike Protein-Specific Antivirals
por: Stelitano, Debora, et al.
Publicado: (2021)

Cooperative Regulation of Campylobacter jejuni Heat-Shock Genes by HspR and HrcA
por: Palombo, Marta, et al.
Publicado: (2020)

Identification of a GrgA-Euo-HrcA Transcriptional Regulatory Network in Chlamydia
por: Wurihan, Wurihan, et al.
Publicado: (2021)

Feeling the Heat: The Campylobacter jejuni HrcA Transcriptional Repressor Is an Intrinsic Protein Thermosensor
por: Versace, Giovanni, et al.
Publicado: (2021)

HRC promotes anoikis resistance and metastasis by suppressing endoplasmic reticulum stress in hepatocellular carcinoma
por: Xia, Suhong, et al.
Publicado: (2021)

Loss of OsHRC function confers blast resistance without yield penalty in rice
por: Ding, Yanpeng, et al.
Publicado: (2023)

Inhibiting Human Parainfluenza Virus Infection by Preactivating the Cell Entry Mechanism
por: Bottom-Tanzer, S. F., et al.
Publicado: (2019)

Spike Glycoprotein and Host Cell Determinants of SARS-CoV-2 Entry and Cytopathic Effects
por: Nguyen, Hanh T., et al.
Publicado: (2021)

Host–pathogen dynamics in longitudinal clinical specimens from patients with COVID-19
por: Lin, Michelle J., et al.
Publicado: (2022)

AAV-Mediated Knock-Down of HRC Exacerbates Transverse Aorta Constriction-Induced Heart Failure
por: Park, Chang Sik, et al.
Publicado: (2012)

Mutagenesis of the transmembrane domain of the SARS coronavirus spike glycoprotein: refinement of the requirements for SARS coronavirus cell entry
por: Corver, Jeroen, et al.
Publicado: (2009)

Inhibition of Nipah Virus Infection In Vivo: Targeting an Early Stage of Paramyxovirus Fusion Activation during Viral Entry
por: Porotto, Matteo, et al.
Publicado: (2010)

Apoptotic-like PCD inducing HRC gene when silenced enhances multiple disease resistance in plants
por: Kushalappa, A. C., et al.
Publicado: (2022)

Furin cleavage of the SARS coronavirus spike glycoprotein enhances cell–cell fusion but does not affect virion entry
por: Follis, Kathryn E., et al.
Publicado: (2006)

Authentic Modeling of Human Respiratory Virus Infection in Human Pluripotent Stem Cell-Derived Lung Organoids
por: Porotto, M., et al.
Publicado: (2019)

Stability of SARS-CoV-2 in Phosphate-Buffered Saline for Molecular Detection
por: Perchetti, Garrett A., et al.
Publicado: (2020)

Synthetic Protocells Interact with Viral Nanomachinery and Inactivate Pathogenic Human Virus
por: Porotto, Matteo, et al.
Publicado: (2011)

HrcQ Provides a Docking Site for Early and Late Type III Secretion Substrates from Xanthomonas
por: Lorenz, Christian, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_u9gvstokmmu4gnhv0763cg50q2