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Lovastatin Differentially Regulates α7 and α4 Neuronal Nicotinic Acetylcholine Receptor Levels in Rat Hippocampal Neurons

Neuronal α7 and α4β2 are the predominant nicotinic acetylcholine receptor (nAChR) subtypes found in the brain, particularly in the hippocampus. The effects of lovastatin, an inhibitor of cholesterol biosynthesis, on these two nAChRs endogenously expressed in rat hippocampal neuronal cells were evalu...

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Detalles Bibliográficos
Autores principales: Borroni, Virginia, Kamerbeek, Constanza, Pediconi, María F., Barrantes, Francisco J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587943/
https://www.ncbi.nlm.nih.gov/pubmed/33092257
http://dx.doi.org/10.3390/molecules25204838

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