Cargando…
The Circular Life of Human CD38: From Basic Science to Clinics and Back
Monoclonal antibodies (mAbs) were initially considered as a possible “magic bullet” for in vivo elimination of tumor cells. mAbs represented the first step: however, as they were murine in nature (the earliest experience on the field), they were considered unfit for human applications. This prompted...
Autores principales: | Horenstein, Alberto L., Faini, Angelo C., Morandi, Fabio, Bracci, Cristiano, Lanza, Francesco, Giuliani, Nicola, Paulus, Aneel, Malavasi, Fabio |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587951/ https://www.ncbi.nlm.nih.gov/pubmed/33096610 http://dx.doi.org/10.3390/molecules25204844 |
Ejemplares similares
-
CD38 in Adenosinergic Pathways and Metabolic Re-programming in Human Multiple Myeloma Cells: In-tandem Insights From Basic Science to Therapy
por: Horenstein, Alberto L., et al.
Publicado: (2019) -
CD38: A Target for Immunotherapeutic Approaches in Multiple Myeloma
por: Morandi, Fabio, et al.
Publicado: (2018) -
CD38, a Receptor with Multifunctional Activities: From Modulatory Functions on Regulatory Cell Subsets and Extracellular Vesicles, to a Target for Therapeutic Strategies
por: Morandi, Fabio, et al.
Publicado: (2019) -
Novel Insights in Anti-CD38 Therapy Based on CD38-Receptor Expression and Function: The Multiple Myeloma Model
por: Zannetti, Beatrice Anna, et al.
Publicado: (2020) -
A non-canonical adenosinergic pathway led by CD38 in human melanoma cells induces suppression of T cell proliferation
por: Morandi, Fabio, et al.
Publicado: (2015)