N-[2-(4-Acetyl-1-Piperazinyl)Phenyl]-2-(3-Methylphenoxy)Acetamide (NAPMA) Inhibits Osteoclast Differentiation and Protects against Ovariectomy-Induced Osteoporosis

Osteoclasts are large, multinucleated cells responsible for bone resorption and are induced in response to the regulatory activity of receptor activator of nuclear factor-kappa B ligand (RANKL). Excessive osteoclast activity causes pathological bone loss and destruction. Many studies have investigat...

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Detalles Bibliográficos
Autores principales: Lee, Jinkyung, Ahn, Sun-Hee, Chen, Zhihao, Kang, Sohi, Choi, Dong Kyu, Moon, Changjong, Min, Sang Hyun, Park, Byung-Ju, Lee, Tae-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587973/
https://www.ncbi.nlm.nih.gov/pubmed/33096734
http://dx.doi.org/10.3390/molecules25204855

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