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Computational Design of Nitrile Hydratase from Pseudonocardia thermophila JCM3095 for Improved Thermostability

High thermostability and catalytic activity are key properties for nitrile hydratase (NHase, EC 4.2.1.84) as a well-industrialized catalyst. In this study, rational design was applied to tailor the thermostability of NHase from Pseudonocardia thermophila JCM3095 (PtNHase) by combining FireProt serve...

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Detalles Bibliográficos
Autores principales:	Cheng, Zhongyi, Lan, Yao, Guo, Junling, Ma, Dong, Jiang, Shijin, Lai, Qianpeng, Zhou, Zhemin, Peplowski, Lukasz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587978/ https://www.ncbi.nlm.nih.gov/pubmed/33086715 http://dx.doi.org/10.3390/molecules25204806

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