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Total Synthesis of Phorbazole B

Phorbazoles are polychlorinated heterocyclic secondary metabolites isolated from a marine sponge and several of these natural products have shown inhibitory activity against cancer cells. In this work, a synthesis of the trichlorinated phorbazole B using late stage electrophilic chlorination was dev...

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Detalles Bibliográficos
Autores principales: Guttormsen, Yngve, Fairhurst, Magnus E., Pandey, Sunil K., Isaksson, Johan, Haug, Bengt Erik, Bayer, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588006/
https://www.ncbi.nlm.nih.gov/pubmed/33096668
http://dx.doi.org/10.3390/molecules25204848