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Fast Estimation of the Blood–Brain Barrier Permeability by Pulling a Ligand through a Lipid Membrane

[Image: see text] The blood–brain barrier (BBB) is a physical barrier that regulates the homeostasis of the neural microenvironment. A relative estimate of the BBB permeability, which is important for drug design, may be experimentally provided by the logBB (the blood–brain concentration ratio) and...

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Detalles Bibliográficos
Autores principales:	Thai, Nguyen Quoc, Theodorakis, Panagiotis E., Li, Mai Suan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588033/ https://www.ncbi.nlm.nih.gov/pubmed/32469527 http://dx.doi.org/10.1021/acs.jcim.9b00834

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