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A non-canonical role for the autophagy machinery in anti-retroviral signaling mediated by TRIM5α

TRIM5α is a key cross-species barrier to retroviral infection, with certain TRIM5 alleles conferring increased risk of HIV-1 infection in humans. TRIM5α is best known as a species-specific restriction factor that directly inhibits the viral life cycle. Additionally, it is also a pattern-recognition...

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Detalles Bibliográficos
Autores principales:	Saha, Bhaskar, Chisholm, Devon, Kell, Alison M., Mandell, Michael A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588057/ https://www.ncbi.nlm.nih.gov/pubmed/33052966 http://dx.doi.org/10.1371/journal.ppat.1009017

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