Maintaining resting cardiac fibroblasts in vitro by disrupting mechanotransduction

Mechanical cues activate cardiac fibroblasts and induce differentiation into myofibroblasts, which are key steps for development of cardiac fibrosis. In vitro, the high stiffness of plastic culturing conditions will also induce these changes. It is therefore challenging to study resting cardiac fibr...

Descripción completa

Detalles Bibliográficos
Autores principales: Gilles, George, McCulloch, Andrew D., Brakebusch, Cord H., Herum, Kate M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588109/
https://www.ncbi.nlm.nih.gov/pubmed/33104742
http://dx.doi.org/10.1371/journal.pone.0241390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588109/
https://www.ncbi.nlm.nih.gov/pubmed/33104742
http://dx.doi.org/10.1371/journal.pone.0241390

Ejemplares similares