Repeated dermal application of the common preservative methylisothiazolinone triggers local inflammation, T cell influx, and prolonged mast cell-dependent tactile sensitivity in mice

Occupational exposure to toxic chemicals increases the risk of developing localized provoked vulvodynia—a prevalent, yet poorly understood, chronic condition characterized by sensitivity to touch and pressure, and accumulation of mast cells in painful tissues. Here, we topically sensitized female ND...

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Detalles Bibliográficos
Autores principales: Kline, Jaclyn M., Arriaga-Gomez, Erica, Yangdon, Tenzin, Boo, Beebie, Landry, Jasmine, Saldías-Montivero, Marietta, Neamonitaki, Nefeli, Mengistu, Hanna, Silverio, Sayira, Zacheis, Hayley, Pasha, Dogukan, Martinov, Tijana, Fife, Brian T., Chatterjea, Devavani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588120/
https://www.ncbi.nlm.nih.gov/pubmed/33104726
http://dx.doi.org/10.1371/journal.pone.0241218

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