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Range of SHH signaling in adrenal gland is limited by membrane contact to cells with primary cilia
The signaling protein Sonic Hedgehog (SHH) is crucial for the development and function of many vertebrate tissues. It remains largely unclear, however, what defines the range and specificity of pathway activation. The adrenal gland represents a useful model to address this question, where the SHH pa...
Autores principales: | Mateska, Ivona, Nanda, Kareena, Dye, Natalie A., Alexaki, Vasileia Ismini, Eaton, Suzanne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588141/ https://www.ncbi.nlm.nih.gov/pubmed/33090184 http://dx.doi.org/10.1083/jcb.201910087 |
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