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Range of SHH signaling in adrenal gland is limited by membrane contact to cells with primary cilia

The signaling protein Sonic Hedgehog (SHH) is crucial for the development and function of many vertebrate tissues. It remains largely unclear, however, what defines the range and specificity of pathway activation. The adrenal gland represents a useful model to address this question, where the SHH pa...

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Detalles Bibliográficos
Autores principales: Mateska, Ivona, Nanda, Kareena, Dye, Natalie A., Alexaki, Vasileia Ismini, Eaton, Suzanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588141/
https://www.ncbi.nlm.nih.gov/pubmed/33090184
http://dx.doi.org/10.1083/jcb.201910087

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