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Structural basis of αE-catenin–F-actin catch bond behavior
Cell-cell and cell-matrix junctions transmit mechanical forces during tissue morphogenesis and homeostasis. α-Catenin links cell-cell adhesion complexes to the actin cytoskeleton, and mechanical load strengthens its binding to F-actin in a direction-sensitive manner. Specifically, optical trap exper...
Autores principales: | Xu, Xiao-Ping, Pokutta, Sabine, Torres, Megan, Swift, Mark F, Hanein, Dorit, Volkmann, Niels, Weis, William I |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588230/ https://www.ncbi.nlm.nih.gov/pubmed/32915141 http://dx.doi.org/10.7554/eLife.60878 |
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