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Time to Cure and Predictors of Recovery Among Children Aged 6–59 Months with Severe Acute Malnutrition Admitted in Jimma University Medical Center, Southwest Ethiopia: A Retrospective Cohort Study

PURPOSE: Treatment at a stabilization center is an important intervention to avert the huge burden of mortality for children with complicated severe acute malnutrition (SAM). Despite the improvement in hospital coverage and the development of standardized WHO treatment guidelines, recent reviews ind...

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Autores principales: Hussen Kabthymer, Robel, Gizaw, Getu, Belachew, Tefera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588275/
https://www.ncbi.nlm.nih.gov/pubmed/33116909
http://dx.doi.org/10.2147/CLEP.S265107
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author Hussen Kabthymer, Robel
Gizaw, Getu
Belachew, Tefera
author_facet Hussen Kabthymer, Robel
Gizaw, Getu
Belachew, Tefera
author_sort Hussen Kabthymer, Robel
collection PubMed
description PURPOSE: Treatment at a stabilization center is an important intervention to avert the huge burden of mortality for children with complicated severe acute malnutrition (SAM). Despite the improvement in hospital coverage and the development of standardized WHO treatment guidelines, recent reviews indicated a wide range in recovery rate (34–88%) due to several context-specific factors. This study aimed to estimate time to recovery and to determine predictors of time to recovery among children aged 6–59 months with severe acute malnutrition. PATIENTS AND METHODS: An institution-based retrospective cohort study design was used among 375 children aged 6–59 months admitted to Jimma University Medical Center, Jimma, Ethiopia from September 2015 to September 2017. All eligible children were enrolled and assessed using a pretested questionnaire. Kaplan–Meir estimates and survival curves were used to compare the time to recovery using log rank test among different characteristics. Cox proportional hazard model was used to identify significant predictors of time to recovery. A p-value less than 0.05 was declared statistically significant. RESULTS: The rate of recovery was 4.06 per 100 person days. Median time of recovery for our cohort of SAM children’s was 19 days (95% CI: 17.95–20.05). Independent predictors of time to recovery were play stimulation (AHR=1.93, 95% CI: 1.23–3.03), vaccination status (AHR=2.26, 95% CI: 1.12–4.57), tuberculosis (AHR= 0.48, 95% CI: 0.27–0.87), malaria (AHR=0.34,95% CI:0.13–0.88), use of amoxicillin (AHR=1.54, 95% CI: 0.008–2.34), deworming (AHR=1.8, 95% CI: 1.18–2.73), and shock (AHR=0.18, 95% CI: 0.05–0.59). CONCLUSION: The findings of this study showed that the average length of stay on treatment and median time for recovery are within the sphere standard. Psychosocial stimulation, appropriate provision of routine medication and management of medical co-morbidity are needed to promote fast recovery.
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spelling pubmed-75882752020-10-27 Time to Cure and Predictors of Recovery Among Children Aged 6–59 Months with Severe Acute Malnutrition Admitted in Jimma University Medical Center, Southwest Ethiopia: A Retrospective Cohort Study Hussen Kabthymer, Robel Gizaw, Getu Belachew, Tefera Clin Epidemiol Original Research PURPOSE: Treatment at a stabilization center is an important intervention to avert the huge burden of mortality for children with complicated severe acute malnutrition (SAM). Despite the improvement in hospital coverage and the development of standardized WHO treatment guidelines, recent reviews indicated a wide range in recovery rate (34–88%) due to several context-specific factors. This study aimed to estimate time to recovery and to determine predictors of time to recovery among children aged 6–59 months with severe acute malnutrition. PATIENTS AND METHODS: An institution-based retrospective cohort study design was used among 375 children aged 6–59 months admitted to Jimma University Medical Center, Jimma, Ethiopia from September 2015 to September 2017. All eligible children were enrolled and assessed using a pretested questionnaire. Kaplan–Meir estimates and survival curves were used to compare the time to recovery using log rank test among different characteristics. Cox proportional hazard model was used to identify significant predictors of time to recovery. A p-value less than 0.05 was declared statistically significant. RESULTS: The rate of recovery was 4.06 per 100 person days. Median time of recovery for our cohort of SAM children’s was 19 days (95% CI: 17.95–20.05). Independent predictors of time to recovery were play stimulation (AHR=1.93, 95% CI: 1.23–3.03), vaccination status (AHR=2.26, 95% CI: 1.12–4.57), tuberculosis (AHR= 0.48, 95% CI: 0.27–0.87), malaria (AHR=0.34,95% CI:0.13–0.88), use of amoxicillin (AHR=1.54, 95% CI: 0.008–2.34), deworming (AHR=1.8, 95% CI: 1.18–2.73), and shock (AHR=0.18, 95% CI: 0.05–0.59). CONCLUSION: The findings of this study showed that the average length of stay on treatment and median time for recovery are within the sphere standard. Psychosocial stimulation, appropriate provision of routine medication and management of medical co-morbidity are needed to promote fast recovery. Dove 2020-10-22 /pmc/articles/PMC7588275/ /pubmed/33116909 http://dx.doi.org/10.2147/CLEP.S265107 Text en © 2020 Hussen Kabthymer et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Hussen Kabthymer, Robel
Gizaw, Getu
Belachew, Tefera
Time to Cure and Predictors of Recovery Among Children Aged 6–59 Months with Severe Acute Malnutrition Admitted in Jimma University Medical Center, Southwest Ethiopia: A Retrospective Cohort Study
title Time to Cure and Predictors of Recovery Among Children Aged 6–59 Months with Severe Acute Malnutrition Admitted in Jimma University Medical Center, Southwest Ethiopia: A Retrospective Cohort Study
title_full Time to Cure and Predictors of Recovery Among Children Aged 6–59 Months with Severe Acute Malnutrition Admitted in Jimma University Medical Center, Southwest Ethiopia: A Retrospective Cohort Study
title_fullStr Time to Cure and Predictors of Recovery Among Children Aged 6–59 Months with Severe Acute Malnutrition Admitted in Jimma University Medical Center, Southwest Ethiopia: A Retrospective Cohort Study
title_full_unstemmed Time to Cure and Predictors of Recovery Among Children Aged 6–59 Months with Severe Acute Malnutrition Admitted in Jimma University Medical Center, Southwest Ethiopia: A Retrospective Cohort Study
title_short Time to Cure and Predictors of Recovery Among Children Aged 6–59 Months with Severe Acute Malnutrition Admitted in Jimma University Medical Center, Southwest Ethiopia: A Retrospective Cohort Study
title_sort time to cure and predictors of recovery among children aged 6–59 months with severe acute malnutrition admitted in jimma university medical center, southwest ethiopia: a retrospective cohort study
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588275/
https://www.ncbi.nlm.nih.gov/pubmed/33116909
http://dx.doi.org/10.2147/CLEP.S265107
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