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The Effects of Body Mass Index on the Use of Patient-Controlled Intravenous Analgesia After Open Gastrointestinal Tumor Surgery: A Retrospective Analysis
PURPOSE: To investigate the impact of body mass index (BMI) on the analgesic effects and adverse reactions of patient-controlled intravenous analgesia (PCIA). METHODS: From 2017 to 2018, 390 patients undergoing open gastrointestinal surgery were reviewed at West China Hospital, Sichuan University. A...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Dove
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588277/ https://www.ncbi.nlm.nih.gov/pubmed/33116809 http://dx.doi.org/10.2147/JPR.S261997 |
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author | Li, Ting-Ting Xiong, Liu-Lin Huang, Jin Wen, Song Chen, Yan-Jun Wang, Ting-Hua Liu, Fei |
author_facet | Li, Ting-Ting Xiong, Liu-Lin Huang, Jin Wen, Song Chen, Yan-Jun Wang, Ting-Hua Liu, Fei |
author_sort | Li, Ting-Ting |
collection | PubMed |
description | PURPOSE: To investigate the impact of body mass index (BMI) on the analgesic effects and adverse reactions of patient-controlled intravenous analgesia (PCIA). METHODS: From 2017 to 2018, 390 patients undergoing open gastrointestinal surgery were reviewed at West China Hospital, Sichuan University. All used PCIA of sufentanil combined with dexmedetomidine and flurbiprofen axetil. According to their BMIs, they were placed into six groups: group A (BMI < 18.5kg/m(2), 29), group B (18.5kg/m(2) ≤ BMI< 22kg/m(2), 124), group C (22kg/m(2) ≤ BMI < 24kg/m(2), 99), group D (24kg/m(2) ≤ BMI < 26kg/m(2), 69), group E (26kg/m(2) ≤ BMI < 28kg/m(2), 46) and group F (BMI ≥28kg/m(2), 23). Main data of the perioperative use of analgesics, postoperative visual analogue score (VAS), and adverse reactions were collected. RESULTS: Twenty-four hours (h) after surgery, patients in group A had a higher resting VAS than the other groups, especially B (p(A-B) = 0.011). VAS of patients during activity in group B was lower than those in group C 48 h after surgery (p = 0.013). Compared with groups B to F, group A had a significantly lower incidence of hypertension (p = 0.012) and a significantly higher incidence of vomiting 24 h after surgery (p = 0.009). Binary logistic analysis found that higher age was a risk factor for vomiting 24 h after surgery (OR 1.158, p = 0.045). CONCLUSION: Using the same PCIA, patients with BMIs of less than 18.5 kg/m(2) had worse analgesia on the first day after surgery and were more likely to vomit. Postoperative analgesia and related experiences in patients with BMIs of less than 18.5 kg/m(2) need to be improved. |
format | Online Article Text |
id | pubmed-7588277 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-75882772020-10-27 The Effects of Body Mass Index on the Use of Patient-Controlled Intravenous Analgesia After Open Gastrointestinal Tumor Surgery: A Retrospective Analysis Li, Ting-Ting Xiong, Liu-Lin Huang, Jin Wen, Song Chen, Yan-Jun Wang, Ting-Hua Liu, Fei J Pain Res Original Research PURPOSE: To investigate the impact of body mass index (BMI) on the analgesic effects and adverse reactions of patient-controlled intravenous analgesia (PCIA). METHODS: From 2017 to 2018, 390 patients undergoing open gastrointestinal surgery were reviewed at West China Hospital, Sichuan University. All used PCIA of sufentanil combined with dexmedetomidine and flurbiprofen axetil. According to their BMIs, they were placed into six groups: group A (BMI < 18.5kg/m(2), 29), group B (18.5kg/m(2) ≤ BMI< 22kg/m(2), 124), group C (22kg/m(2) ≤ BMI < 24kg/m(2), 99), group D (24kg/m(2) ≤ BMI < 26kg/m(2), 69), group E (26kg/m(2) ≤ BMI < 28kg/m(2), 46) and group F (BMI ≥28kg/m(2), 23). Main data of the perioperative use of analgesics, postoperative visual analogue score (VAS), and adverse reactions were collected. RESULTS: Twenty-four hours (h) after surgery, patients in group A had a higher resting VAS than the other groups, especially B (p(A-B) = 0.011). VAS of patients during activity in group B was lower than those in group C 48 h after surgery (p = 0.013). Compared with groups B to F, group A had a significantly lower incidence of hypertension (p = 0.012) and a significantly higher incidence of vomiting 24 h after surgery (p = 0.009). Binary logistic analysis found that higher age was a risk factor for vomiting 24 h after surgery (OR 1.158, p = 0.045). CONCLUSION: Using the same PCIA, patients with BMIs of less than 18.5 kg/m(2) had worse analgesia on the first day after surgery and were more likely to vomit. Postoperative analgesia and related experiences in patients with BMIs of less than 18.5 kg/m(2) need to be improved. Dove 2020-10-22 /pmc/articles/PMC7588277/ /pubmed/33116809 http://dx.doi.org/10.2147/JPR.S261997 Text en © 2020 Li et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Original Research Li, Ting-Ting Xiong, Liu-Lin Huang, Jin Wen, Song Chen, Yan-Jun Wang, Ting-Hua Liu, Fei The Effects of Body Mass Index on the Use of Patient-Controlled Intravenous Analgesia After Open Gastrointestinal Tumor Surgery: A Retrospective Analysis |
title | The Effects of Body Mass Index on the Use of Patient-Controlled Intravenous Analgesia After Open Gastrointestinal Tumor Surgery: A Retrospective Analysis |
title_full | The Effects of Body Mass Index on the Use of Patient-Controlled Intravenous Analgesia After Open Gastrointestinal Tumor Surgery: A Retrospective Analysis |
title_fullStr | The Effects of Body Mass Index on the Use of Patient-Controlled Intravenous Analgesia After Open Gastrointestinal Tumor Surgery: A Retrospective Analysis |
title_full_unstemmed | The Effects of Body Mass Index on the Use of Patient-Controlled Intravenous Analgesia After Open Gastrointestinal Tumor Surgery: A Retrospective Analysis |
title_short | The Effects of Body Mass Index on the Use of Patient-Controlled Intravenous Analgesia After Open Gastrointestinal Tumor Surgery: A Retrospective Analysis |
title_sort | effects of body mass index on the use of patient-controlled intravenous analgesia after open gastrointestinal tumor surgery: a retrospective analysis |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588277/ https://www.ncbi.nlm.nih.gov/pubmed/33116809 http://dx.doi.org/10.2147/JPR.S261997 |
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