Cargando…

Markers of neutrophil activation and extracellular traps formation are predictive of appendicitis in mice and humans: a pilot study

Appendicitis is one of the most frequent emergencies in pediatric surgery, yet current biomarkers for diagnosis are unspecific and have low predictive values. As neutrophils and extracellular traps (ETs) are an essential component of the immune defense against bacterial infections, and appendicitis...

Descripción completa

Detalles Bibliográficos
Autores principales:	Boettcher, Michael, Esser, Melina, Trah, Julian, Klohs, Stefan, Mokhaberi, Nariman, Wenskus, Julia, Trochimiuk, Madgalena, Appl, Birgit, Reinshagen, Konrad, Raluy, Laia Pagerols, Klinke, Michaela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588418/ https://www.ncbi.nlm.nih.gov/pubmed/33106536 http://dx.doi.org/10.1038/s41598-020-74370-9

Ejemplares similares

The Inhibitory Effect of Curosurf(®) and Alveofact(®) on the Formation of Neutrophil Extracellular Traps
por: Schulz, Annabell, et al.
Publicado: (2021)

Time- and dose-dependent inhibition of neutrophil extracellular trap formation by blocking of the interleukin-1 receptor
por: Wadehn, Hannah, et al.
Publicado: (2021)

Development of an improved murine model of necrotizing enterocolitis shows the importance of neutrophils in NEC pathogenesis
por: Klinke, Michaela, et al.
Publicado: (2020)

Therapeutic Targeting of Neutrophil Extracellular Traps Improves Primary and Secondary Intention Wound Healing in Mice
por: Heuer, Annika, et al.
Publicado: (2021)

NET Release of Long-Term Surviving Neutrophils
por: Kolman, Jan Philipp, et al.
Publicado: (2022)

Lithocholic bile acid induces apoptosis in human nephroblastoma cells: a non-selective treatment option
por: Trah, Julian, et al.
Publicado: (2020)

Neutrophil extracellular traps and DNases orchestrate formation of peritoneal adhesions
por: Elrod, Julia, et al.
Publicado: (2023)

Biliatresone induces cholangiopathy in C57BL/6J neonates
por: Schmidt, Hans Christian, et al.
Publicado: (2023)

Cardiac and Inflammatory Necrotizing Enterocolitis in Newborns Are Not the Same Entity
por: Klinke, Michaela, et al.
Publicado: (2021)

Murine scald models characterize the role of neutrophils and neutrophil extracellular traps in severe burns
por: Elrod, Julia, et al.
Publicado: (2023)

NEC is likely a NETs dependent process and markers of NETosis are predictive of NEC in mice and humans
por: Vincent, Deirdre, et al.
Publicado: (2018)

Midgut Volvulus Adds a Murine, Neutrophil-Driven Model of Septic Condition to the Experimental Toolbox
por: Elrod, Julia, et al.
Publicado: (2023)

The role of neutrophil extracellular traps in necrotizing enterocolitis
por: Klinke, Michaela, et al.
Publicado: (2023)

Sensitization of neuroblastoma for vincristine-induced apoptosis by Smac mimetic LCL161 is attended by G2 cell cycle arrest but is independent of NFκB, RIP1 and TNF-α
por: Langemann, Doerte, et al.
Publicado: (2017)

The Modified Heidelberg and the AI Appendicitis Score Are Superior to Current Scores in Predicting Appendicitis in Children: A Two-Center Cohort Study
por: Stiel, Carolin, et al.
Publicado: (2020)

Markers of NETosis Do Not Predict Neonatal Early Onset Sepsis: A Pilot Study
por: Stiel, Carolin U., et al.
Publicado: (2020)

The BAL-Score Almost Perfectly Predicts Testicular Torsion in Children: A Two-Center Cohort Study
por: Klinke, Michaela, et al.
Publicado: (2020)

Smac mimetic LCL161 supports neuroblastoma chemotherapy in a drug class-dependent manner and synergistically interacts with ALK inhibitor TAE684 in cells with ALK mutation F1174L
por: Najem, Safiullah, et al.
Publicado: (2016)

Abdominal Wall Movements Predict Intra-Abdominal Pressure Changes in Rats: A Novel Non-Invasive Intra-Abdominal Pressure Detection Method
por: Vincent, Deirdre, et al.
Publicado: (2023)

Pediatric surgery and self-reported anxiety in children and their parents: A psychometric analysis of the state-trait operation anxiety (STOA) questionnaire
por: Barkmann, Claus, et al.
Publicado: (2023)

Low gestational age is associated with less anastomotic complications after open primary repair of esophageal atresia with tracheoesophageal fistula
por: Dingemann, Carmen, et al.
Publicado: (2020)

Integra(®)-Dermal Regeneration Template and Split-Thickness Skin Grafting: A Therapy Approach to Correct Aplasia Cutis Congenita and Epidermolysis Bullosa in Carmi Syndrome
por: Trah, Julian, et al.
Publicado: (2018)

Infantile Hepatic Hemangioma: Avoiding Unnecessary Invasive Procedures
por: Ernst, Lukas, et al.
Publicado: (2020)

Effects of Educational Video on Pre-operative Anxiety in Children - A Randomized Controlled Trial
por: Härter, Valentina, et al.
Publicado: (2021)

Therapeutic targeting of extracellular DNA improves the outcome of intestinal ischemic reperfusion injury in neonatal rats
por: Boettcher, Michael, et al.
Publicado: (2017)

Appendicitis and Peritonitis in Children with a Ventriculo-Peritoneal Shunt
por: Fröschle, Glenn M. C., et al.
Publicado: (2023)

Myeloperoxidase Deficiency Alters the Process of the Regulated Cell Death of Polymorphonuclear Neutrophils
por: Kremserová, Silvie, et al.
Publicado: (2022)

Delta neutrophil index as an early predictor of acute appendicitis and acute complicated appendicitis in adults
por: Shin, Dong Hyuk, et al.
Publicado: (2017)

Limits in Laparoscopic Partial Splenectomy in Children
por: Tomuschat, Christian, et al.
Publicado: (2022)

Clinical outcome, quality of life, and mental health in long-gap esophageal atresia: comparison of gastric sleeve pull-up and delayed primary anastomosis
por: Boettcher, Michael, et al.
Publicado: (2023)

Neutrophil Extracellular Traps and Microcrystals
por: Rada, Balázs
Publicado: (2017)

Neutrophil Extracellular Traps in Periodontitis
por: Magán-Fernández, Antonio, et al.
Publicado: (2020)

Phagocytosis and neutrophil extracellular traps
por: DeLeo, Frank R, et al.
Publicado: (2020)

Autophagy in Neutrophils: From Granulopoiesis to Neutrophil Extracellular Traps
por: Skendros, Panagiotis, et al.
Publicado: (2018)

Excessive Neutrophils and Neutrophil Extracellular Traps in COVID-19
por: Wang, Jun, et al.
Publicado: (2020)

The Role of Neutrophils and Neutrophil Extracellular Traps in Acute Pancreatitis
por: Wan, Jianhua, et al.
Publicado: (2021)

Perceived mental health in parents of children with rare congenital surgical diseases: a double ABCX model considering gender
por: Boettcher, Johannes, et al.
Publicado: (2021)

Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps
por: Papayannopoulos, Venizelos, et al.
Publicado: (2010)

The Neutrophil’s Choice: Phagocytose vs Make Neutrophil Extracellular Traps
por: Manfredi, Angelo A., et al.
Publicado: (2018)

Neutrophils and Neutrophil Extracellular Traps Drive Necroinflammation in COVID-19
por: Tomar, Bhawna, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_k62vro1p8e6palhq9ds53r0d6f