Slug regulates the Dll4-Notch-VEGFR2 axis to control endothelial cell activation and angiogenesis

Slug (SNAI2), a member of the well-conserved Snail family of transcription factors, has multiple developmental roles, including in epithelial-to-mesenchymal transition (EMT). Here, we show that Slug is critical for the pathological angiogenesis needed to sustain tumor growth, and transiently necessa...

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Detalles Bibliográficos
Autores principales: Hultgren, Nan W., Fang, Jennifer S., Ziegler, Mary E., Ramirez, Ricardo N., Phan, Duc T. T., Hatch, Michaela M. S., Welch-Reardon, Katrina M., Paniagua, Antonio E., Kim, Lin S., Shon, Nathan N., Williams, David S., Mortazavi, Ali, Hughes, Christopher C. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588439/
https://www.ncbi.nlm.nih.gov/pubmed/33106502
http://dx.doi.org/10.1038/s41467-020-18633-z

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