Disruption of Tip60 HAT mediated neural histone acetylation homeostasis is an early common event in neurodegenerative diseases

Epigenetic dysregulation is a common mechanism shared by molecularly and clinically heterogenous neurodegenerative diseases (NDs). Histone acetylation homeostasis, maintained by the antagonistic activity of histone acetyltransferases (HATs) and histone deacetylases (HDACs), is necessary for appropri...

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Detalles Bibliográficos
Autores principales: Beaver, Mariah, Bhatnagar, Akanksha, Panikker, Priyalakshmi, Zhang, Haolin, Snook, Renee, Parmar, Visha, Vijayakumar, Gayathri, Betini, Niteesha, Akhter, Sunya, Elefant, Felice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588445/
https://www.ncbi.nlm.nih.gov/pubmed/33106538
http://dx.doi.org/10.1038/s41598-020-75035-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588445/
https://www.ncbi.nlm.nih.gov/pubmed/33106538
http://dx.doi.org/10.1038/s41598-020-75035-3

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