SARS-CoV-2 Virus Culture and Subgenomic RNA for Respiratory Specimens from Patients with Mild Coronavirus Disease

We investigated 68 respiratory specimens from 35 coronavirus disease patients in Hong Kong, of whom 32 had mild disease. We found that severe acute respiratory syndrome coronavirus 2 and subgenomic RNA were rarely detectable beyond 8 days after onset of illness. However, virus RNA was detectable for...

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Autores principales: Perera, Ranawaka A.P.M., Tso, Eugene, Tsang, Owen T.Y., Tsang, Dominic N.C., Fung, Kitty, Leung, Yonna W.Y., Chin, Alex W.H., Chu, Daniel K.W., Cheng, Samuel M.S., Poon, Leo L.M., Chuang, Vivien W.M., Peiris, Malik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2020
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588524/
https://www.ncbi.nlm.nih.gov/pubmed/32749957
http://dx.doi.org/10.3201/eid2611.203219
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author Perera, Ranawaka A.P.M.
Tso, Eugene
Tsang, Owen T.Y.
Tsang, Dominic N.C.
Fung, Kitty
Leung, Yonna W.Y.
Chin, Alex W.H.
Chu, Daniel K.W.
Cheng, Samuel M.S.
Poon, Leo L.M.
Chuang, Vivien W.M.
Peiris, Malik
author_facet Perera, Ranawaka A.P.M.
Tso, Eugene
Tsang, Owen T.Y.
Tsang, Dominic N.C.
Fung, Kitty
Leung, Yonna W.Y.
Chin, Alex W.H.
Chu, Daniel K.W.
Cheng, Samuel M.S.
Poon, Leo L.M.
Chuang, Vivien W.M.
Peiris, Malik
author_sort Perera, Ranawaka A.P.M.
collection PubMed
description We investigated 68 respiratory specimens from 35 coronavirus disease patients in Hong Kong, of whom 32 had mild disease. We found that severe acute respiratory syndrome coronavirus 2 and subgenomic RNA were rarely detectable beyond 8 days after onset of illness. However, virus RNA was detectable for many weeks by reverse transcription PCR.
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spelling pubmed-75885242020-11-01 SARS-CoV-2 Virus Culture and Subgenomic RNA for Respiratory Specimens from Patients with Mild Coronavirus Disease Perera, Ranawaka A.P.M. Tso, Eugene Tsang, Owen T.Y. Tsang, Dominic N.C. Fung, Kitty Leung, Yonna W.Y. Chin, Alex W.H. Chu, Daniel K.W. Cheng, Samuel M.S. Poon, Leo L.M. Chuang, Vivien W.M. Peiris, Malik Emerg Infect Dis Dispatch We investigated 68 respiratory specimens from 35 coronavirus disease patients in Hong Kong, of whom 32 had mild disease. We found that severe acute respiratory syndrome coronavirus 2 and subgenomic RNA were rarely detectable beyond 8 days after onset of illness. However, virus RNA was detectable for many weeks by reverse transcription PCR. Centers for Disease Control and Prevention 2020-11 /pmc/articles/PMC7588524/ /pubmed/32749957 http://dx.doi.org/10.3201/eid2611.203219 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Perera, Ranawaka A.P.M.
Tso, Eugene
Tsang, Owen T.Y.
Tsang, Dominic N.C.
Fung, Kitty
Leung, Yonna W.Y.
Chin, Alex W.H.
Chu, Daniel K.W.
Cheng, Samuel M.S.
Poon, Leo L.M.
Chuang, Vivien W.M.
Peiris, Malik
SARS-CoV-2 Virus Culture and Subgenomic RNA for Respiratory Specimens from Patients with Mild Coronavirus Disease
title SARS-CoV-2 Virus Culture and Subgenomic RNA for Respiratory Specimens from Patients with Mild Coronavirus Disease
title_full SARS-CoV-2 Virus Culture and Subgenomic RNA for Respiratory Specimens from Patients with Mild Coronavirus Disease
title_fullStr SARS-CoV-2 Virus Culture and Subgenomic RNA for Respiratory Specimens from Patients with Mild Coronavirus Disease
title_full_unstemmed SARS-CoV-2 Virus Culture and Subgenomic RNA for Respiratory Specimens from Patients with Mild Coronavirus Disease
title_short SARS-CoV-2 Virus Culture and Subgenomic RNA for Respiratory Specimens from Patients with Mild Coronavirus Disease
title_sort sars-cov-2 virus culture and subgenomic rna for respiratory specimens from patients with mild coronavirus disease
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588524/
https://www.ncbi.nlm.nih.gov/pubmed/32749957
http://dx.doi.org/10.3201/eid2611.203219
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