μDamID: A Microfluidic Approach for Joint Imaging and Sequencing of Protein-DNA Interactions in Single Cells

DNA adenine methyltransferase identification (DamID) measures a protein’s DNA-binding history by methylating adenine bases near each protein-DNA interaction site and then selectively amplifying and sequencing these methylated regions. Additionally, these interactions can be visualized using (m6)A-Tr...

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Detalles Bibliográficos
Autores principales: Altemose, Nicolas, Maslan, Annie, Rios-Martinez, Carolina, Lai, Andre, White, Jonathan A., Streets, Aaron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588622/
https://www.ncbi.nlm.nih.gov/pubmed/33099405
http://dx.doi.org/10.1016/j.cels.2020.08.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588622/
https://www.ncbi.nlm.nih.gov/pubmed/33099405
http://dx.doi.org/10.1016/j.cels.2020.08.015

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