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μDamID: A Microfluidic Approach for Joint Imaging and Sequencing of Protein-DNA Interactions in Single Cells
DNA adenine methyltransferase identification (DamID) measures a protein’s DNA-binding history by methylating adenine bases near each protein-DNA interaction site and then selectively amplifying and sequencing these methylated regions. Additionally, these interactions can be visualized using (m6)A-Tr...
Autores principales: | Altemose, Nicolas, Maslan, Annie, Rios-Martinez, Carolina, Lai, Andre, White, Jonathan A., Streets, Aaron |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588622/ https://www.ncbi.nlm.nih.gov/pubmed/33099405 http://dx.doi.org/10.1016/j.cels.2020.08.015 |
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