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Thrombotic Complications in Venous Malformations: Are There Differences Between Facial and Other Localizations?
Venous thrombosis (VT) is a frequent complication in venous malformations (VM) in relation with blood stasis and localized intravascular coagulopathy (LIC). Our aim was to describe the clinical characteristics and the treatment of patients with facial and non facial VM with VT. We implemented an obs...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588756/ https://www.ncbi.nlm.nih.gov/pubmed/33085511 http://dx.doi.org/10.1177/1076029620968143 |
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author | Soudet, Simon Dakpe, Stephanie Le Gloan, Sandra Carmi, Esther Arnault, Jean Philippe Testelin, Sylvie Plancq, Marie-Christine Devauchelle, Bernard Sevestre, Marie Antoinette |
author_facet | Soudet, Simon Dakpe, Stephanie Le Gloan, Sandra Carmi, Esther Arnault, Jean Philippe Testelin, Sylvie Plancq, Marie-Christine Devauchelle, Bernard Sevestre, Marie Antoinette |
author_sort | Soudet, Simon |
collection | PubMed |
description | Venous thrombosis (VT) is a frequent complication in venous malformations (VM) in relation with blood stasis and localized intravascular coagulopathy (LIC). Our aim was to describe the clinical characteristics and the treatment of patients with facial and non facial VM with VT. We implemented an observational retrospective study of patients with VM followed between 2002 and 2017. We compared features of facial and non facial VM. Descriptive and bivariate statistics were computed and the P value was set at 0.05. Fifty patients were included between 2002 and 2017. 24 of them were women (44%). The median age of the patients at diagnosis was 16,5 [8-31] years. The median follow up was 2 [2; 4] years. In non facial VM venous thrombosis occurred in 12 cases. In facial VM, 3 patients had thrombotic complication (15%). We demonstrate no difference of VT between facial VM and other localization. No patients had clinical risk factors for VT at diagnosis. Our study showed that VT is a frequent complication of VM and its proportion is not different between facial and non facial VM. Studies are needed to confirm the role of LIC in VT in VM, particularly in facial VM. |
format | Online Article Text |
id | pubmed-7588756 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-75887562020-11-09 Thrombotic Complications in Venous Malformations: Are There Differences Between Facial and Other Localizations? Soudet, Simon Dakpe, Stephanie Le Gloan, Sandra Carmi, Esther Arnault, Jean Philippe Testelin, Sylvie Plancq, Marie-Christine Devauchelle, Bernard Sevestre, Marie Antoinette Clin Appl Thromb Hemost Original Article Venous thrombosis (VT) is a frequent complication in venous malformations (VM) in relation with blood stasis and localized intravascular coagulopathy (LIC). Our aim was to describe the clinical characteristics and the treatment of patients with facial and non facial VM with VT. We implemented an observational retrospective study of patients with VM followed between 2002 and 2017. We compared features of facial and non facial VM. Descriptive and bivariate statistics were computed and the P value was set at 0.05. Fifty patients were included between 2002 and 2017. 24 of them were women (44%). The median age of the patients at diagnosis was 16,5 [8-31] years. The median follow up was 2 [2; 4] years. In non facial VM venous thrombosis occurred in 12 cases. In facial VM, 3 patients had thrombotic complication (15%). We demonstrate no difference of VT between facial VM and other localization. No patients had clinical risk factors for VT at diagnosis. Our study showed that VT is a frequent complication of VM and its proportion is not different between facial and non facial VM. Studies are needed to confirm the role of LIC in VT in VM, particularly in facial VM. SAGE Publications 2020-10-21 /pmc/articles/PMC7588756/ /pubmed/33085511 http://dx.doi.org/10.1177/1076029620968143 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Original Article Soudet, Simon Dakpe, Stephanie Le Gloan, Sandra Carmi, Esther Arnault, Jean Philippe Testelin, Sylvie Plancq, Marie-Christine Devauchelle, Bernard Sevestre, Marie Antoinette Thrombotic Complications in Venous Malformations: Are There Differences Between Facial and Other Localizations? |
title | Thrombotic Complications in Venous Malformations: Are There
Differences Between Facial and Other Localizations? |
title_full | Thrombotic Complications in Venous Malformations: Are There
Differences Between Facial and Other Localizations? |
title_fullStr | Thrombotic Complications in Venous Malformations: Are There
Differences Between Facial and Other Localizations? |
title_full_unstemmed | Thrombotic Complications in Venous Malformations: Are There
Differences Between Facial and Other Localizations? |
title_short | Thrombotic Complications in Venous Malformations: Are There
Differences Between Facial and Other Localizations? |
title_sort | thrombotic complications in venous malformations: are there
differences between facial and other localizations? |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588756/ https://www.ncbi.nlm.nih.gov/pubmed/33085511 http://dx.doi.org/10.1177/1076029620968143 |
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