Tumor cell endogenous HIF-1α activity induces aberrant angiogenesis and interacts with TRAF6 pathway required for colorectal cancer development

Hypoxia and inflammation are key factors for colorectal cancer tumorigenesis. The colonic epithelium belongs to the tissues with the lowest partial pressure of oxygen in the body, and chronic inflammation is associated with an increased chance to develop colon cancer. How the colonic epithelium resp...

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Detalles Bibliográficos
Autores principales: Glaus Garzon, Jesus F., Pastrello, Chiara, Jurisica, Igor, Hottiger, Michael O., Wenger, Roland H., Borsig, Lubor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588814/
https://www.ncbi.nlm.nih.gov/pubmed/33142239
http://dx.doi.org/10.1016/j.neo.2020.10.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588814/
https://www.ncbi.nlm.nih.gov/pubmed/33142239
http://dx.doi.org/10.1016/j.neo.2020.10.006

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