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Identification of novel therapeutic targets for blocking acantholysis in pemphigus

BACKGROUND AND PURPOSE: Pemphigus is caused by autoantibodies against desmoglein (Dsg) 1, Dsg3, and/or non‐Dsg antigens. Pemphigus vulgaris (PV) is the most common manifestation of pemphigus, with painful erosions on mucous membranes. In most cases, blistering also occurs on the skin, leading to are...

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Detalles Bibliográficos
Autores principales: Burmester, Imke A.K., Flaswinkel, Sarah, Thies, Clara‐Sophie, Kasprick, Anika, Kamaguchi, Mayumi, Bumiller‐Bini, Valéria, Emtenani, Shirin, Feldmann, Nick, Kridin, Khalaf, Schmidt, Enno, van Beek, Nina, Zillikens, Detlef, Hammers, Christoph M., Hundt, Jennifer E., Ludwig, Ralf J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588822/
https://www.ncbi.nlm.nih.gov/pubmed/32815159
http://dx.doi.org/10.1111/bph.15233