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Pharmacological Inhibition of ATR Can Block Autophagy through an ATR-Independent Mechanism
Inhibition of the ATR kinase has emerged as a therapeutically attractive means to target cancer since the development of potent inhibitors, which are now in clinical testing. We investigated a potential link between ATR inhibition and the autophagy process in esophageal cancer cells using four ATR i...
Autores principales: | Bowler, Elizabeth, Skwarska, Anna, Wilson, Joseph D., Ramachandran, Shaliny, Bolland, Hannah, Easton, Alistair, Ostheimer, Christian, Hwang, Ming-Shih, Leszczynska, Katarzyna B., Conway, Stuart J., Hammond, Ester M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588853/ https://www.ncbi.nlm.nih.gov/pubmed/33134898 http://dx.doi.org/10.1016/j.isci.2020.101668 |
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