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Molecular Basis for Polyketide Ketoreductase–Substrate Interactions

Polyketides are a large class of structurally and functionally diverse natural products with important bioactivities. Many polyketides are synthesized by reducing type II polyketide synthases (PKSs), containing transiently interacting standalone enzymes. During synthesis, ketoreductase (KR) catalyze...

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Detalles Bibliográficos
Autores principales:	Zhao, Shiji, Ni, Fanglue, Qiu, Tianyin, Wolff, Jacob T., Tsai, Shiou-Chuan, Luo, Ray
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588967/ https://www.ncbi.nlm.nih.gov/pubmed/33066287 http://dx.doi.org/10.3390/ijms21207562

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