Physicochemical, Pharmacokinetic, and Toxicity Evaluation of Soluplus(®) Polymeric Micelles Encapsulating Fenbendazole

Fenbendazole (FEN), a broad-spectrum benzimidazole anthelmintic, suppresses cancer cell growth through various mechanisms but has low solubility and achieves low blood concentrations, which leads to low bioavailability. Solubilizing agents are required to prepare poorly soluble drugs for injections;...

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Detalles Bibliográficos
Autores principales: Jin, Ik Sup, Jo, Min Jeong, Park, Chun-Woong, Chung, Youn Bok, Kim, Jin-Seok, Shin, Dae Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589096/
https://www.ncbi.nlm.nih.gov/pubmed/33096915
http://dx.doi.org/10.3390/pharmaceutics12101000

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589096/
https://www.ncbi.nlm.nih.gov/pubmed/33096915
http://dx.doi.org/10.3390/pharmaceutics12101000

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