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Combining Surface Templating and Confinement for Controlling Pharmaceutical Crystallization
Poor water solubility is one of the major challenges to the development of oral dosage forms containing active pharmaceutical ingredients (APIs). Polymorphism in APIs leads to crystals with different surface wettabilities and free energies, which can lead to different dissolution properties. Crystal...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589131/ https://www.ncbi.nlm.nih.gov/pubmed/33092148 http://dx.doi.org/10.3390/pharmaceutics12100995 |