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Chymase as a Possible Therapeutic Target for Amelioration of Non-Alcoholic Steatohepatitis
The development and progression of non-alcoholic steatohepatitis (NASH) are linked to oxidative stress, inflammation, and fibrosis of the liver. Chymase, a chymotrypsin-like enzyme produced in mast cells, has various enzymatic actions. These actions include activation of angiotensin II, matrix metal...
Autores principales: | Takai, Shinji, Jin, Denan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589185/ https://www.ncbi.nlm.nih.gov/pubmed/33066113 http://dx.doi.org/10.3390/ijms21207543 |
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