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Cryogenic OrbiSIMS Localizes Semi‐Volatile Molecules in Biological Tissues
OrbiSIMS is a recently developed instrument for label‐free imaging of chemicals with micron spatial resolution and high mass resolution. We report a cryogenic workflow for OrbiSIMS (Cryo‐OrbiSIMS) that improves chemical detection of lipids and other biomolecules in tissues. Cryo‐OrbiSIMS boosts ioni...
Autores principales: | Newell, Clare L., Vorng, Jean‐Luc, MacRae, James I., Gilmore, Ian S., Gould, Alex P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589292/ https://www.ncbi.nlm.nih.gov/pubmed/32603009 http://dx.doi.org/10.1002/anie.202006881 |
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