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Nrf2 Lowers the Risk of Lung Injury via Modulating the Airway Innate Immune Response Induced by Diesel Exhaust in Mice
In the present study, we investigated the role of Nrf2 in airway immune responses induced by diesel exhaust (DE) inhalation in mice. C57BL/6J Nrf2(+/+) and Nrf2(−/−) mice were exposed to DE or clean air for 8 h/day and 6 days/week for 4 weeks. After DE exposure, the number of neutrophils and macroph...
Autores principales: | Li, Ying-Ji, Shimizu, Takako, Shinkai, Yusuke, Ihara, Tomomi, Sugamata, Masao, Kato, Katsuhito, Kobayashi, Maiko, Hirata, Yukiyo, Inagaki, Hirofumi, Uzuki, Makoto, Akimoto, Toshio, Umezawa, Masakazu, Takeda, Ken, Azuma, Arata, Yamamoto, Masayuki, Kawada, Tomoyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589508/ https://www.ncbi.nlm.nih.gov/pubmed/33096811 http://dx.doi.org/10.3390/biomedicines8100443 |
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