DDX3 DEAD-box RNA helicase (Hel67) gene disruption impairs infectivity of Leishmania donovani and induces protective immunity against visceral leishmaniasis

Visceral leishmaniasis (VL) is a vector-borne disease caused by the digenetic protozoan parasite Leishmania donovani complex. So far there is no effective vaccine available against VL. The DDX3 DEAD-box RNA Helicase (Hel67) is 67 kDa protein which is quite essential for RNA metabolism, amastigote di...

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Detalles Bibliográficos
Autores principales: Pandey, Satish Chandra, Pande, Veena, Samant, Mukesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589518/
https://www.ncbi.nlm.nih.gov/pubmed/33106577
http://dx.doi.org/10.1038/s41598-020-75420-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589518/
https://www.ncbi.nlm.nih.gov/pubmed/33106577
http://dx.doi.org/10.1038/s41598-020-75420-y

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