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Breast tumor cells promotes the horizontal propagation of EMT, stemness, and metastasis by transferring the MAP17 protein between subsets of neoplastic cells

MAP17 (PDZK1IP1) is a small protein regulating inflammation and tumor progression, upregulated in a broad range of carcinomas. MAP17 levels increase during tumor progression in a large percentage of advanced tumors. In the present work, we explored the role of this protein shaping tumor evolution. H...

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Detalles Bibliográficos
Autores principales: García-Heredia, José Manuel, Otero-Albiol, Daniel, Pérez, Marco, Pérez-Castejón, Elena, Muñoz-Galván, Sandra, Carnero, Amancio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589521/
https://www.ncbi.nlm.nih.gov/pubmed/33106480
http://dx.doi.org/10.1038/s41389-020-00280-0