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Nitroxides Mitigate Neutrophil-Mediated Damage to the Myocardium after Experimental Myocardial Infarction in Rats
Reperfusion therapy increases survival post-acute myocardial infarction (AMI) while also stimulating secondary oxidant production and immune cell infiltration. Neutrophils accumulate within infarcted myocardium within 24 h post-AMI and release myeloperoxidase (MPO) that catalyses hypochlorous acid (...
Autores principales: | El Kazzi, Mary, Shi, Han, Vuong, Sally, Wang, Xiaosuo, Chami, Belal, Liu, Yuyang, Rayner, Benjamin S., Witting, Paul K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589606/ https://www.ncbi.nlm.nih.gov/pubmed/33081101 http://dx.doi.org/10.3390/ijms21207650 |
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