The HLA Variant rs6903608 Is Associated with Disease Onset and Relapse of Immune-Mediated Thrombotic Thrombocytopenic Purpura in Caucasians

Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is a rare, life-threatening thrombotic microangiopathy caused by severe ADAMTS13 (a disintegrin and metalloproteinase with thrombospondin motifs 13) deficiency, recurring in 30–50% of patients. The common human leukocyte antigen (HLA) varian...

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Autores principales: Mancini, Ilaria, Giacomini, Elisa, Pontiggia, Silvia, Artoni, Andrea, Ferrari, Barbara, Pappalardo, Emanuela, Gualtierotti, Roberta, Trisolini, Silvia Maria, Capria, Saveria, Facchini, Luca, Codeluppi, Katia, Rinaldi, Erminia, Pastore, Domenico, Campus, Simona, Caria, Cinzia, Caddori, Aldo, Nicolosi, Daniela, Giuffrida, Gaetano, Agostini, Vanessa, Roncarati, Umberto, Mannarella, Clara, Fragasso, Alberto, Podda, Gian Marco, Birocchi, Simone, Cerbone, Anna Maria, Tufano, Antonella, Menna, Giuseppe, Pizzuti, Michele, Ronchi, Michela, De Fanti, Alessandro, Amarri, Sergio, Defina, Marzia, Bocchia, Monica, Cerù, Silvia, Gattillo, Salvatore, Rosendaal, Frits R., Peyvandi, Flora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589625/
https://www.ncbi.nlm.nih.gov/pubmed/33096882
http://dx.doi.org/10.3390/jcm9103379

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