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Disruption of Zika Virus xrRNA1-Dependent sfRNA1 Production Results in Tissue-Specific Attenuated Viral Replication

The Zika virus (ZIKV), like other flaviviruses, produces several species of sub-genomic RNAs (sfRNAs) during infection, corresponding to noncoding RNA fragments of different lengths that result from the exonuclease degradation of the viral 3′ untranslated region (UTR). Over the course of infection,...

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Detalles Bibliográficos
Autores principales: Sparks, Hadrian, Monogue, Brendan, Akiyama, Benjamin, Kieft, Jeffrey, Beckham, J. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589627/
https://www.ncbi.nlm.nih.gov/pubmed/33080971
http://dx.doi.org/10.3390/v12101177