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Disruption of Zika Virus xrRNA1-Dependent sfRNA1 Production Results in Tissue-Specific Attenuated Viral Replication
The Zika virus (ZIKV), like other flaviviruses, produces several species of sub-genomic RNAs (sfRNAs) during infection, corresponding to noncoding RNA fragments of different lengths that result from the exonuclease degradation of the viral 3′ untranslated region (UTR). Over the course of infection,...
Autores principales: | Sparks, Hadrian, Monogue, Brendan, Akiyama, Benjamin, Kieft, Jeffrey, Beckham, J. David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589627/ https://www.ncbi.nlm.nih.gov/pubmed/33080971 http://dx.doi.org/10.3390/v12101177 |
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