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Reversal of Ovarian Cancer Cell Lines Multidrug Resistance Phenotype by the Association of Apiole with Chemotherapies

Multidrug resistance (MDR) is the main obstacle in anticancer therapy. The use of drug combinations to circumvent tumor resistance is a well-established principle in the clinic. Among the therapeutic targets, glycoprotein-P (P-gp), an energy-dependent transmembrane efflux pump responsible for modula...

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Detalles Bibliográficos
Autores principales: Afonso de Lima, Carolina, de Souza Bueno, Ian Lucas, Nunes Siqueira Vasconcelos, Stanley, Sciani, Juliana Mozer, Ruiz, Ana Lúcia Tasca Gois, Foglio, Mary Ann, de Carvalho, João Ernesto, Barbarini Longato, Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589691/
https://www.ncbi.nlm.nih.gov/pubmed/33096917
http://dx.doi.org/10.3390/ph13100327