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Resveratrol Rescue Indoxyl Sulfate-Induced Deterioration of Osteoblastogenesis via the Aryl Hydrocarbon Receptor /MAPK Pathway
Indoxyl sulfate (IS), a uremic toxin derived from dietary tryptophan metabolism by the gut microbiota, is an endogenous aryl hydrocarbon receptor (AhR) agonist and a key player in bone remodeling. Resveratrol (RSV), an AhR antagonist, plays a protective role in shielding against AhR ligands. Our stu...
Autores principales: | Liu, Wen-Chih, Shyu, Jia-Fwu, Lin, Yuh-Feng, Chiu, Hui-Wen, Lim, Paik Seong, Lu, Chien-Lin, Zheng, Cai-Mei, Hou, Yi-Chou, Chen, Po-Han, Lu, Kuo-Cheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589702/ https://www.ncbi.nlm.nih.gov/pubmed/33050571 http://dx.doi.org/10.3390/ijms21207483 |
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