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Recombinant Bacillus caldovelox Arginase Mutant (BCA-M) Induces Apoptosis, Autophagy, Cell Cycle Arrest and Growth Inhibition in Human Cervical Cancer Cells

With our recent success in developing a recombinant human arginase drug against broad-spectrum cancer cell lines, we have explored the potential of a recombinant Bacillus caldovelox arginase mutant (BCA-M) for human cervical cancer treatment. Our studies demonstrated that BCA-M significantly inhibit...

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Detalles Bibliográficos
Autores principales: Chung, Sai-Fung, Kim, Chi-Fai, Chow, Ho-Yin, Chong, Hiu-Chi, Tam, Suet-Ying, Leung, Yun-Chung, Lo, Wai-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589785/
https://www.ncbi.nlm.nih.gov/pubmed/33050217
http://dx.doi.org/10.3390/ijms21207445