Cargando…

NLRP3 as Putative Marker of Ipilimumab-Induced Cardiotoxicity in the Presence of Hyperglycemia in Estrogen-Responsive and Triple-Negative Breast Cancer Cells

Hyperglycemia, obesity and metabolic syndrome are negative prognostic factors in breast cancer patients. Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment, achieving unprecedented efficacy in multiple malignancies. However, ICIs are associated with immune-related adverse event...

Descripción completa

Detalles Bibliográficos
Autores principales:	Quagliariello, Vincenzo, De Laurentiis, Michelino, Cocco, Stefania, Rea, Giuseppina, Bonelli, Annamaria, Caronna, Antonietta, Lombari, Maria Cristina, Conforti, Gabriele, Berretta, Massimiliano, Botti, Gerardo, Maurea, Nicola
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589802/ https://www.ncbi.nlm.nih.gov/pubmed/33096896 http://dx.doi.org/10.3390/ijms21207802

Ejemplares similares

SARS-CoV-2 Infection and Cardioncology: From Cardiometabolic Risk Factors to Outcomes in Cancer Patients
por: Quagliariello, Vincenzo, et al.
Publicado: (2020)

Evidences of CTLA-4 and PD-1 Blocking Agents-Induced Cardiotoxicity in Cellular and Preclinical Models
por: Quagliariello, Vincenzo, et al.
Publicado: (2020)

Polydatin Reduces Cardiotoxicity and Enhances the Anticancer Effects of Sunitinib by Decreasing Pro-Oxidative Stress, Pro-Inflammatory Cytokines, and NLRP3 Inflammasome Expression
por: Quagliariello, Vincenzo, et al.
Publicado: (2021)

The SGLT-2 inhibitor empagliflozin improves myocardial strain, reduces cardiac fibrosis and pro-inflammatory cytokines in non-diabetic mice treated with doxorubicin
por: Quagliariello, Vincenzo, et al.
Publicado: (2021)

Cardioprotective Effects of Nanoemulsions Loaded with Anti-Inflammatory Nutraceuticals against Doxorubicin-Induced Cardiotoxicity
por: Quagliariello, Vincenzo, et al.
Publicado: (2018)

Combination of Spirulina platensis, Ganoderma lucidum and Moringa oleifera Improves Cardiac Functions and Reduces Pro-Inflammatory Biomarkers in Preclinical Models of Short-Term Doxorubicin-Mediated Cardiotoxicity: New Frontiers in Cardioncology?
por: Quagliariello, Vincenzo, et al.
Publicado: (2022)

PCSK9 Inhibitors in Cancer Patients Treated with Immune-Checkpoint Inhibitors to Reduce Cardiovascular Events: New Frontiers in Cardioncology
por: Quagliariello, Vincenzo, et al.
Publicado: (2023)

Antineoplastic-related cardiotoxicity, morphofunctional aspects in a murine model: contribution of the new tool 2D-speckle tracking
por: Coppola, Carmela, et al.
Publicado: (2016)

Cardiotoxic effects of the novel approved anti-ErbB2 agents and reverse cardioprotective effects of ranolazine
por: De Lorenzo, Claudia, et al.
Publicado: (2018)

Long Non-Coding RNA HOTAIR in Breast Cancer Therapy
por: Cantile, Monica, et al.
Publicado: (2020)

A recommended practical approach to the management of anthracycline-based chemotherapy cardiotoxicity: an opinion paper of the working group on drug cardiotoxicity and cardioprotection, Italian Society of Cardiology
por: Spallarossa, Paolo, et al.
Publicado: (2016)

A meta-analytic review of the relationship of cancer coping self-efficacy with distress and quality of life
por: Chirico, Andrea, et al.
Publicado: (2017)

A recommended practical approach to the management of target therapy and angiogenesis inhibitors cardiotoxicity: an opinion paper of the working group on drug cardiotoxicity and cardioprotection, Italian Society of Cardiology
por: Maurea, Nicola, et al.
Publicado: (2016)

Resveratrol in Cancer Patients: From Bench to Bedside
por: Berretta, Massimiliano, et al.
Publicado: (2020)

Nano-Encapsulation of Coenzyme Q10 in Secondary and Tertiary Nano-Emulsions for Enhanced Cardioprotection and Hepatoprotection in Human Cardiomyocytes and Hepatocytes During Exposure to Anthracyclines and Trastuzumab
por: Quagliariello, Vincenzo, et al.
Publicado: (2020)

Biomarkers in Triple-Negative Breast Cancer: State-of-the-Art and Future Perspectives
por: Cocco, Stefania, et al.
Publicado: (2020)

The role of taxanes in triple-negative breast cancer: literature review
por: Mustacchi, Giorgio, et al.
Publicado: (2015)

Rare tumours of the breast
por: Esposito, Emanuela, et al.
Publicado: (2019)

Active lifestyles in older adults: an integrated predictive model of physical activity and exercise
por: Galli, Federica, et al.
Publicado: (2018)

Ipilimumab
Publicado: (2012)

Immune checkpoint inhibitor therapy increases systemic SDF-1, cardiac DAMPs Fibronectin-EDA, S100/Calgranulin, galectine-3, and NLRP3-MyD88-chemokine pathways
por: Quagliariello, Vincenzo, et al.
Publicado: (2022)

Corrigendum: Immune checkpoint inhibitor therapy increases systemic SDF-1, cardiac DAMPs Fibronectin-EDA, S100/Calgranulin, galectine-3, and NLRP3-MyD88-chemokine pathways
por: Quagliariello, Vincenzo, et al.
Publicado: (2023)

Targeting Cell Cycle in Breast Cancer: CDK4/6 Inhibitors
por: Piezzo, Michela, et al.
Publicado: (2020)

Metabolic syndrome-breast cancer link varies by intrinsic molecular subtype
por: Capasso, Immacolata, et al.
Publicado: (2014)

Combination of inositol and alpha lipoic acid in metabolic syndrome-affected women: a randomized placebo-controlled trial
por: Capasso, Immacolata, et al.
Publicado: (2013)

CB1R-stabilized NLRP3 inflammasome drives antipsychotics cardiotoxicity
por: Li, Liliang, et al.
Publicado: (2022)

Multiple Effects of Ascorbic Acid against Chronic Diseases: Updated Evidence from Preclinical and Clinical Studies
por: Berretta, Massimiliano, et al.
Publicado: (2020)

Targeting Autophagy in Breast Cancer
por: Cocco, Stefania, et al.
Publicado: (2020)

Improved Survival and Quality of Life Through an Integrative, Multidisciplinary Oncological Approach: Pathophysiological Analysis of Four Clinical Cancer Cases and Review of the Literature
por: Berretta, M., et al.
Publicado: (2022)

Melatonin attenuates AFB1-induced cardiotoxicity via the NLRP3 signalling pathway
por: Yan, Hui, et al.
Publicado: (2020)

Calycosin Alleviates Doxorubicin-Induced Cardiotoxicity and Pyroptosis by Inhibiting NLRP3 Inflammasome Activation
por: Zhang, Lei, et al.
Publicado: (2022)

LncRNA HOTAIR up-regulation is strongly related with lymph nodes metastasis and LAR subtype of Triple Negative Breast Cancer
por: Collina, Francesca, et al.
Publicado: (2019)

Male Breast Cancer: From Molecular Genetics to Clinical Management
por: Pensabene, Matilde, et al.
Publicado: (2022)

MISIPI study: Melanoma ImmunoScore evaluation in patients treated with IPIlimumab
por: Bifulco, Carlo, et al.
Publicado: (2014)

Ipilimumab in the treatment of metastatic melanoma: management of adverse events
por: Della Vittoria Scarpati, Giuseppina, et al.
Publicado: (2014)

Prognostic Value of Cancer Stem Cells Markers in Triple-Negative Breast Cancer
por: Collina, Francesca, et al.
Publicado: (2015)

Targeting Oxidative Stress, NLRP3 Inflammasome, and Autophagy by Fraxetin to Combat Doxorubicin-Induced Cardiotoxicity
por: Kabel, Ahmed M., et al.
Publicado: (2021)

Automatic discovery of image-based signatures for ipilimumab response prediction in malignant melanoma
por: Harder, Nathalie, et al.
Publicado: (2019)

How to Optimise Extended Adjuvant Treatment with Neratinib for Patients with Early HER2+ Breast Cancer
por: Untch, Michael, et al.
Publicado: (2021)

Ipilimumab: Melanoma and beyond
por: Patel, Vishal, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_jjvf9lugdghk8hiqtuf8r7sola