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Enhanced Lymphatic Delivery of Methotrexate Using W/O/W Nanoemulsion: In Vitro Characterization and Pharmacokinetic Study

Methotrexate, which is widely used in the treatment of cancer and immune-related diseases, has limitations in use because of its low bioavailability, short half-life, and tissue toxicity. Thus, in this study, a nano-sized water-in-oil-in-water (W/O/W) double emulsion containing methotrexate was prep...

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Detalles Bibliográficos
Autores principales:	Jang, Ji-Hun, Jeong, Seung-Hyun, Lee, Yong-Bok
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589886/ https://www.ncbi.nlm.nih.gov/pubmed/33081266 http://dx.doi.org/10.3390/pharmaceutics12100978

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