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Towards Reduction or Substitution of Cytotoxic DMSO in Biobanking of Functional Bioengineered Megakaryocytes

Donor platelet transfusion is currently the only efficient treatment of life-threatening thrombocytopenia, but it is highly challenged by immunological, quality, and contamination issues, as well as short shelf life of the donor material. Ex vivo produced megakaryocytes and platelets represent a pro...

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Detalles Bibliográficos
Autores principales: Pogozhykh, Denys, Eicke, Dorothee, Gryshkov, Oleksandr, Wolkers, Willem F., Schulze, Kai, Guzmán, Carlos A., Blasczyk, Rainer, Figueiredo, Constança
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589913/
https://www.ncbi.nlm.nih.gov/pubmed/33081128
http://dx.doi.org/10.3390/ijms21207654