Cargando…

Towards Reduction or Substitution of Cytotoxic DMSO in Biobanking of Functional Bioengineered Megakaryocytes

Donor platelet transfusion is currently the only efficient treatment of life-threatening thrombocytopenia, but it is highly challenged by immunological, quality, and contamination issues, as well as short shelf life of the donor material. Ex vivo produced megakaryocytes and platelets represent a pro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pogozhykh, Denys, Eicke, Dorothee, Gryshkov, Oleksandr, Wolkers, Willem F., Schulze, Kai, Guzmán, Carlos A., Blasczyk, Rainer, Figueiredo, Constança
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589913/ https://www.ncbi.nlm.nih.gov/pubmed/33081128 http://dx.doi.org/10.3390/ijms21207654

Ejemplares similares

Characterization of induced pluripotent stem cell‐derived megakaryocyte lysates for potential regenerative applications
por: Baigger, Anja, et al.
Publicado: (2018)

Large-scale production of megakaryocytes in microcarrier-supported stirred suspension bioreactors
por: Eicke, Dorothee, et al.
Publicado: (2018)

Repeated Freezing Procedures Preserve Structural and Functional Properties of Amniotic Membrane for Application in Ophthalmology
por: Pogozhykh, Olena, et al.
Publicado: (2020)

Generation of HLA Universal Megakaryocytes and Platelets by Genetic Engineering
por: Figueiredo, Constanca, et al.
Publicado: (2021)

Encapsulating Non-Human Primate Multipotent Stromal Cells in Alginate via High Voltage for Cell-Based Therapies and Cryopreservation
por: Gryshkov, Oleksandr, et al.
Publicado: (2014)

Placenta and Placental Derivatives in Regenerative Therapies: Experimental Studies, History, and Prospects
por: Pogozhykh, Olena, et al.
Publicado: (2018)

Molecular and cellular characteristics of human and non-human primate multipotent stromal cells from the amnion and bone marrow during long term culture
por: Pogozhykh, Olena, et al.
Publicado: (2015)

Influence of temperature fluctuations during cryopreservation on vital parameters, differentiation potential, and transgene expression of placental multipotent stromal cells
por: Pogozhykh, Denys, et al.
Publicado: (2017)

Storage stability of liposomes stored at elevated subzero temperatures in DMSO/sucrose mixtures
por: Sydykov, Bulat, et al.
Publicado: (2018)

Low immunogenic endothelial cells endothelialize the Left Ventricular Assist Device
por: Figueiredo, Constanca, et al.
Publicado: (2019)

Generating low immunogenic pig pancreatic islet cell clusters for xenotransplantation
por: Carvalho Oliveira, Marco, et al.
Publicado: (2020)

Increasing storage stability of freeze-dried plasma using trehalose
por: Brogna, Raffaele, et al.
Publicado: (2020)

Bioengineered Scaffolds as Substitutes for Grafts for Urethra Reconstruction
por: Culenova, Martina, et al.
Publicado: (2019)

HSP70 Enhances Immunosuppressive Function of CD4(+)CD25(+)FoxP3(+) T Regulatory Cells and Cytotoxicity in CD4(+)CD25(−) T Cells
por: Wachstein, Julian, et al.
Publicado: (2012)

Energy Relaxation and Structural Dynamics of Protons in Water/DMSO Mixtures
por: Sofronov, Oleksandr O., et al.
Publicado: (2018)

Microwave Sensor for the Determination of DMSO Concentration in Water–DMSO Binary Mixture
por: Harnsoongnoen, Supakorn, et al.
Publicado: (2023)

From Grafts to Human Bioengineered Vascularized Skin Substitutes
por: Oualla-Bachiri, Wasima, et al.
Publicado: (2020)

Downregulation of Swine Leukocyte Antigen Expression Decreases the Strength of Xenogeneic Immune Responses towards Renal Proximal Tubular Epithelial Cells
por: Schmalkuche, Katharina, et al.
Publicado: (2023)

Influence of Factors of Cryopreservation and Hypothermic Storage on Survival and Functional Parameters of Multipotent Stromal Cells of Placental Origin
por: Pogozhykh, Denys, et al.
Publicado: (2015)

First Iridium(IV) Chloride–Dimethyl Sulfoxide Complex [H(dmso)(2)][IrCl(5)(dmso-κO)]: Synthesis and Structure along with Novel Polymorph Modifications of [H(dmso)(2)][trans-IrCl(4)(dmso-κS)(2)] and [H(dmso)][trans-IrCl(4)(dmso-κS)(2)]
por: Rudnitskaya, Olga V., et al.
Publicado: (2023)

Microstructural free volume and dynamics of cryoprotective DMSO–water mixtures at low DMSO concentration
por: Čechová, Katarína, et al.
Publicado: (2019)

Epidermal Basement Membrane Substitutes for Bioengineering of Human Epidermal Equivalents
por: Kolundzic, Nikola, et al.
Publicado: (2021)

Secreted β(3)-Integrin Enhances Natural Killer Cell Activity against Acute Myeloid Leukemia Cells
por: Skaik, Younis, et al.
Publicado: (2014)

MHC Universal Cells Survive in an Allogeneic Environment after Incompatible Transplantation
por: Figueiredo, Constança, et al.
Publicado: (2013)

The Persecuted Drug. The Story of DMSO
por: McGuire, Joseph
Publicado: (1975)

Cytotoxicity, Epidermal Barrier Function and Cytokine Evaluation after Antiseptic Treatment in Bioengineered Autologous Skin Substitute
por: García-Valdivia, Marta, et al.
Publicado: (2022)

Weak Interactions in Dimethyl Sulfoxide (DMSO)–Tertiary Amide Solutions: The Versatility of DMSO as a Solvent
por: Di Mino, Camilla, et al.
Publicado: (2023)

DMSO reduces the cytotoxicity of anticancer ruthenium complex KP1019 in yeast
por: Davis, Jonathan, et al.
Publicado: (2021)

Advancement of wound care from grafts to bioengineered smart skin substitutes
por: Augustine, Robin, et al.
Publicado: (2014)

Human megakaryocytes. V. Changes in the phenotypic profile of differentiating megakaryocytes
Publicado: (1985)

Hungry megakaryocytes on the hunt? An unusual case of extensive megakaryocyte emperipolesis
por: Vijaya Devi, S., et al.
Publicado: (2021)

Effect of DMSO on lifespan and physiology in C. elegans : Implications for use of DMSO as a solvent for compound delivery
por: AlOkda, Abdelrahman, et al.
Publicado: (2022)

DMSO modulates the pathway of apoptosis triggering
por: Banič, Blaž, et al.
Publicado: (2011)

Hydrogenation of CO(2) to Formic Acid with a Highly Active Ruthenium Acriphos Complex in DMSO and DMSO/Water
por: Rohmann, Kai, et al.
Publicado: (2016)

Dissolution of Cellulose in Ionic Liquid–DMSO Mixtures: Roles of DMSO/IL Ratio and the Cation Alkyl Chain Length
por: Ren, Fei, et al.
Publicado: (2021)

Human megakaryocytes. II. Expression of platelet proteins in early marrow megakaryocytes
Publicado: (1981)

Discovery of immunodominant T-cell epitopes reveals penton protein as a second immunodominant target in human adenovirus infection
por: Tischer, Sabine, et al.
Publicado: (2016)

Collagen-Based Bioengineered Substitutes of Donor Corneal Allograft Implantation: Assessment and Hypotheses
por: Pasyechnikova, Nataliya, et al.
Publicado: (2012)

Dermal Matrices and Bioengineered Skin Substitutes: A Critical Review of Current Options
por: Debels, Heidi, et al.
Publicado: (2015)

Bioengineered Skin Substitutes: The Role of Extracellular Matrix and Vascularization in the Healing of Deep Wounds
por: Urciuolo, Francesco, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_aktufv0s90rp7i4avols99e4tp