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Adjuvant Antitumor Immunity Contributes to the Overall Antitumor Effect of Pegylated Liposomal Doxorubicin (Doxil(®)) in C26 Tumor-Bearing Immunocompetent Mice

Doxorubicin (DXR) has been reported to have direct cytotoxicity against cancer cells and indirect immunotoxicity by modulation of host antitumor immunity. Hence, it may prevent cancer progression by a dual mechanism. Doxil(®), a formulation of DXR encapsulated in polyethylene glycol modified (PEGyla...

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Detalles Bibliográficos
Autores principales: Takayama, Takuma, Shimizu, Taro, Abu Lila, Amr S., Kanazawa, Yuki, Ando, Hidenori, Ishima, Yu, Ishida, Tatsuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589973/
https://www.ncbi.nlm.nih.gov/pubmed/33086690
http://dx.doi.org/10.3390/pharmaceutics12100990

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