Development of Conformational Antibodies to Detect Bcl-xL’s Amyloid Aggregates in Metal-Induced Apoptotic Neuroblastoma Cells

Bcl-xL, a member of the Bcl-2 family, is a pro-survival protein involved in apoptosis regulation. We have previously reported the ability of Bcl-xL to form various types of fibers, from native to amyloid conformations. Here, we have mimicked the effect of apoptosis-induced caspase activity on Bcl-xL...

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Detalles Bibliográficos
Autores principales: Gonneaud, Alexis, Fakhir, Fatima-Zohra, Landas, Emeline, Le Tallec, Enora, Chartier-Garcia, Elisabeth, Almunia, Christine, Chenal, Alexandre, Forge, Vincent, Marquette, Christel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589975/
https://www.ncbi.nlm.nih.gov/pubmed/33076337
http://dx.doi.org/10.3390/ijms21207625

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