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Serotonin Transporter and Plasma Membrane Monoamine Transporter Are Necessary for the Antidepressant-Like Effects of Ketamine in Mice

Major depressive disorder is typically treated with selective serotonin reuptake inhibitors (SSRIs), however, SSRIs take approximately six weeks to produce therapeutic effects, if any. Not surprisingly, there has been great interest in findings that low doses of ketamine, a non-competitive N-methyl-...

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Detalles Bibliográficos
Autores principales: Bowman, Melodi A., Vitela, Melissa, Clarke, Kyra M., Koek, Wouter, Daws, Lynette C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589995/
https://www.ncbi.nlm.nih.gov/pubmed/33066466
http://dx.doi.org/10.3390/ijms21207581

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