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Therapeutic Implications for PDE2 and cGMP/cAMP Mediated Crosstalk in Cardiovascular Diseases

Phosphodiesterases (PDEs) are the principal superfamily of enzymes responsible for degrading the secondary messengers 3′,5′-cyclic nucleotides cAMP and cGMP. Their refined subcellular localization and substrate specificity contribute to finely regulate cAMP/cGMP gradients in various cellular microdo...

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Detalles Bibliográficos
Autores principales:	Sadek, Mirna S., Cachorro, Eleder, El-Armouche, Ali, Kämmerer, Susanne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590001/ https://www.ncbi.nlm.nih.gov/pubmed/33050419 http://dx.doi.org/10.3390/ijms21207462

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