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A retrospective cohort study of adverse event assessment during anesthesia‐related procedures for cochlear implant candidacy assessment and cochlear implantation in infants and toddlers

BACKGROUND: Cochlear implantation in children with sensorineural hearing loss is preferably performed at youngest age because early auditory input is essential to prevent neural plasticity decline. In contrast, the rate of anesthetic adverse events is increased during infancy. Therefore, to provide...

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Autores principales: Bruijnzeel, Hanneke, Wammes, Emily, Stokroos, Robert J., Topsakal, Vedat, de Graaff, Jurgen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590089/
https://www.ncbi.nlm.nih.gov/pubmed/32506586
http://dx.doi.org/10.1111/pan.13944
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author Bruijnzeel, Hanneke
Wammes, Emily
Stokroos, Robert J.
Topsakal, Vedat
de Graaff, Jurgen C.
author_facet Bruijnzeel, Hanneke
Wammes, Emily
Stokroos, Robert J.
Topsakal, Vedat
de Graaff, Jurgen C.
author_sort Bruijnzeel, Hanneke
collection PubMed
description BACKGROUND: Cochlear implantation in children with sensorineural hearing loss is preferably performed at youngest age because early auditory input is essential to prevent neural plasticity decline. In contrast, the rate of anesthetic adverse events is increased during infancy. Therefore, to provide recommendations regarding an optimal pediatric implantation age, these possible anesthetic risks in infants need to be taken into account. AIMS: This study aimed at assessing the relation between the age at cochlear implant surgery and anesthetic and surgical adverse events. Secondary aims were to evaluate anesthetic and surgical adverse events in relation to (a) the number of preoperative anesthesia‐related procedures for cochlear implant candidacy assessment and (b) the anesthetic maintenance agent (total intravenous anesthesia versus inhalation anesthesia) during implantation. METHODS: We executed a retrospective cohort study to evaluate cochlear implantation performed in infants and toddlers between January 2008 and July 2015 in a tertiary pediatric center. We compared anesthetic and surgical adverse events between age‐at‐implantation (0‐12 and 12‐24 months of age) groups. Furthermore, we assessed whether anesthetic adverse events occurred during preoperative anesthesia‐related procedures for cochlear implant candidacy assessment. RESULTS: Forty‐six cochlear implantations were performed in 43 patients requiring 42 preoperative anesthesia‐related procedures. Nineteen cochlear implantations (41.3%) were performed during infancy. During implantation, the maintenance agent was either sevoflurane (n = 22) or propofol (n = 24). None of the patients encountered major anesthetic adverse events, whereas minor adverse events occurred during 34 cochlear implantations. Those attributed to surgery occurred following six implantations. Neither the age at implantation nor the anesthetic maintenance agent was significantly related to the occurrence of both types of adverse events. CONCLUSIONS: Adverse events occur independent of the age at implantation, the number of anesthetic preoperative procedures, and the type of anesthetic maintenance agent in patients who received a cochlear implant before 24 months of age.
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spelling pubmed-75900892020-10-30 A retrospective cohort study of adverse event assessment during anesthesia‐related procedures for cochlear implant candidacy assessment and cochlear implantation in infants and toddlers Bruijnzeel, Hanneke Wammes, Emily Stokroos, Robert J. Topsakal, Vedat de Graaff, Jurgen C. Paediatr Anaesth Research Reports BACKGROUND: Cochlear implantation in children with sensorineural hearing loss is preferably performed at youngest age because early auditory input is essential to prevent neural plasticity decline. In contrast, the rate of anesthetic adverse events is increased during infancy. Therefore, to provide recommendations regarding an optimal pediatric implantation age, these possible anesthetic risks in infants need to be taken into account. AIMS: This study aimed at assessing the relation between the age at cochlear implant surgery and anesthetic and surgical adverse events. Secondary aims were to evaluate anesthetic and surgical adverse events in relation to (a) the number of preoperative anesthesia‐related procedures for cochlear implant candidacy assessment and (b) the anesthetic maintenance agent (total intravenous anesthesia versus inhalation anesthesia) during implantation. METHODS: We executed a retrospective cohort study to evaluate cochlear implantation performed in infants and toddlers between January 2008 and July 2015 in a tertiary pediatric center. We compared anesthetic and surgical adverse events between age‐at‐implantation (0‐12 and 12‐24 months of age) groups. Furthermore, we assessed whether anesthetic adverse events occurred during preoperative anesthesia‐related procedures for cochlear implant candidacy assessment. RESULTS: Forty‐six cochlear implantations were performed in 43 patients requiring 42 preoperative anesthesia‐related procedures. Nineteen cochlear implantations (41.3%) were performed during infancy. During implantation, the maintenance agent was either sevoflurane (n = 22) or propofol (n = 24). None of the patients encountered major anesthetic adverse events, whereas minor adverse events occurred during 34 cochlear implantations. Those attributed to surgery occurred following six implantations. Neither the age at implantation nor the anesthetic maintenance agent was significantly related to the occurrence of both types of adverse events. CONCLUSIONS: Adverse events occur independent of the age at implantation, the number of anesthetic preoperative procedures, and the type of anesthetic maintenance agent in patients who received a cochlear implant before 24 months of age. John Wiley and Sons Inc. 2020-07-30 2020-09 /pmc/articles/PMC7590089/ /pubmed/32506586 http://dx.doi.org/10.1111/pan.13944 Text en © 2020 The Authors. Pediatric Anesthesia published by John Wiley & Sons Ltd This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Research Reports
Bruijnzeel, Hanneke
Wammes, Emily
Stokroos, Robert J.
Topsakal, Vedat
de Graaff, Jurgen C.
A retrospective cohort study of adverse event assessment during anesthesia‐related procedures for cochlear implant candidacy assessment and cochlear implantation in infants and toddlers
title A retrospective cohort study of adverse event assessment during anesthesia‐related procedures for cochlear implant candidacy assessment and cochlear implantation in infants and toddlers
title_full A retrospective cohort study of adverse event assessment during anesthesia‐related procedures for cochlear implant candidacy assessment and cochlear implantation in infants and toddlers
title_fullStr A retrospective cohort study of adverse event assessment during anesthesia‐related procedures for cochlear implant candidacy assessment and cochlear implantation in infants and toddlers
title_full_unstemmed A retrospective cohort study of adverse event assessment during anesthesia‐related procedures for cochlear implant candidacy assessment and cochlear implantation in infants and toddlers
title_short A retrospective cohort study of adverse event assessment during anesthesia‐related procedures for cochlear implant candidacy assessment and cochlear implantation in infants and toddlers
title_sort retrospective cohort study of adverse event assessment during anesthesia‐related procedures for cochlear implant candidacy assessment and cochlear implantation in infants and toddlers
topic Research Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590089/
https://www.ncbi.nlm.nih.gov/pubmed/32506586
http://dx.doi.org/10.1111/pan.13944
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